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Many of the following conditions commonly occur in conjunction with each other and all have been linked to magnesium (Mg) deficiency.
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Patents with fibromyalgia and chronic fatigue syndrome are often found to be low in Mg. Supplementation with malic acid and magnesium is a common treatment for fibromyalgia.
Seventy-five percent of the people with fibromyalgia have mitral valve prolapse. Mitral valve prolapse is thought to occur in about 10% of the population in general, so this statistically is quite significant. Mitral valve prolapse is another disorder also closely linked to Mg deficiency.
Hypermobility is also closely linked to fibromyalgia. Hypermobility is a feature of rickets which has links to Mg deficiencies.
Women with fibromyalgia have been found to have abnormal serum levels of hyaluronic acid. The authors of this study suggested serum hyaluronic levels may be used to diagnose fibromyalgia. But are elevated serum hyaluronic acid levels an indicator of fibromyalgia, or are they yet another symptom of a Mg deficiency?
Interestingly, people with Down syndrome have elevated serum hyaluronic acid levels, too. What are some common links between Down syndrome and fibromyalgia? Both groups have mitral valve prolapse and hypermobility at rates much higher rates than controls, and Down syndrome patients have been found to be low in magnesium, among other trace elements.
Fibromyalgia, hypermobility and mitral valve prolapse are closely linked to each other, all may be linked to magnesium deficiency and all are features of many chronic disorders, and virtually all hereditary connective tissue disorders, especially Ehlers-Danlos syndrome. All three conditions are also features of Down syndrome, which has many overlaps with connective tissue disorders. All of these individual features and syndromes are linked to hyaluronic acid abnormalities, and hyaluronic acid is dependent upon Mg for its synthesis.
Magnesium deficiency, and perhaps other elements that affect hyaluronic acid levels, are a common thread to connective tissue disorders and disorders with overlapping features like Down syndrome. If these disorders all had an underlying biochemical deficiency such a magnesium deficit, then all of these interesting associations between mitral valve prolapse, fibromyalgia, hyaluronic acid, magnesium, Down syndrome and connective tissue disorders would have perfectly logical explanations.
Click here to go to my fibromaylagia diet page.
Also see my separate section on mitral valve prolapse for information on why studies show a strong link between fibromyalgia and MVP.
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